Differential Effects of Commercial-Grade and Purified Poloxamer 188 on Renal Function

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Differential Effects of Commercial-Grade and Purified Poloxamer 188 on Renal Function

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer with hemorheologic, antithrombotic, anti-inflammatory, and cytoprotective properties. It potentially has clinical utility in diverse diseases, such as acute myocardial infarction, acute limb ischemia, shock, acute stroke, heart failure, and sickle cell crisis. P188 is available as an excipient-grade product, manufactured to National Form...

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ژورنال

عنوان ژورنال: Drugs in R&D

سال: 2014

ISSN: 1174-5886,1179-6901

DOI: 10.1007/s40268-014-0041-0